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US Patent 8012482 Humanized anti-TGF-beta antibodies

Patent 8012482 was granted and assigned to Genentech on September, 2011 by the United States Patent and Trademark Office.

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Current Assignee

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

Patent Inventor Names

Camellia W. Adams0

Ellen Filvaroff0

Leonard G. Presta0

Max L. Tejada0

Napoleone Ferrara0

Weiguang Mao0

Date of Patent

September 6, 2011

Patent Application Number

12423664

Date Filed

April 14, 2009

Patent Citations Received

US Patent 11701384 Methods and compositions involving interleukin-6 receptor alpha-binding single chain variable fragments

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US Patent 11944648 Bispecific OR-gate chimeric antigen receptor responsive to CD19 and CD20

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US Patent 11919948 Isoform-selective anti-TGFβ antibodies and methods of use

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Patent Primary Examiner

Shulamith H. Shafer

Patent abstract

Humanized anti-TGF-beta antibodies are provided, as well as methods for their preparation and use, including methods for treating TGF-beta disorders, for example, cancer. Also provided are articles of manufacture designed for various uses that contain the humanized antibodies.

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