US Patent 8008446 Auto-antibodies against the melanocortin-4 receptor

Patent 8008446 was granted and assigned to University of Basel on August, 2011 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

University of Basel

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

8008446

Date of Patent

August 30, 2011

Patent Application Number

12347153

Date Filed

December 31, 2008

Patent Primary Examiner

‌

Shulamith H. Shafer

Patent abstract

Disclosed are biological markers for obesity and methods for diagnosing and treating obesity and related conditions by detecting and modulating the activity of auto-antibodies against the melanocortin-4 receptor or a portion of the melanocortin-4 receptor. Also disclosed are methods for discovering new therapeutics which modulate the activity of auto-antibodies against the melanocortin-4 receptor or a portion of the melanocortin-4 receptor, in particular which prevent the binding of auto-antibodies against the melanocortin-4 receptor or a portion of the melanocortin-4 receptor.