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Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
David B. Rozema0
Jon A. Wolff0
James E. Hagstrom0
Sean D. Monahan0
Lori Higgs0
Darren H. Wakefield0
Date of Patent
August 30, 2011
Patent Application Number
12140681
Date Filed
June 17, 2008
Patent Primary Examiner
Patent abstract
The present invention is directed to membrane active polymers useful for cellular delivery of compounds. Described are polyconjugates systems that incorporate targeting, anti-opsonization, anti-aggregation, and transfection activities into small biocompatible in vivo delivery conjugates. The use of reversible modification provides for physiologically responsive activity modulation.
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