Patent 8003780 was granted and assigned to Neomics Co., Ltd. on August, 2011 by the United States Patent and Trademark Office.
The present invention relates to a variant of AIMP2 lacking exon 2 gene, named as AIMP2-DX2 gene, which is specifically expressed in cancer cells. The AIMP2-DX2 gene and siRNA targeting AIMP2-DX2 can be successfully used in the development of diagnosis and treatment of cancer.