US Patent 7998941 Hypoxia inducible VEGF plasmid for ischemic disease

Patent 7998941 was granted and assigned to University of Utah on August, 2011 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

University of Utah

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

79989410

Patent Inventor Names

Sung Wan Kim0

Minhyung Lee0

Date of Patent

August 16, 2011

Patent Application Number

126491410

Date Filed

December 29, 2009

Patent Primary Examiner

‌

Brian Whiteman

Patent abstract

Plasmids useful for treating ischemic disease, such as ischemic heart disease, are described. The plasmids express vascular endothelial growth factor (VEGF) under the control of a promoter (RTP801) that is up-regulated under hypoxic conditions. Pharmaceutical compositions for treating ischemic disease include mixtures of the hypoxia-regulated VEGF plasmids and pharmaceutically acceptable carriers. Methods for treating ischemic disease include administering such pharmaceutical compositions to a person in need of such treatment.