US Patent 7989469 Certain chemical entities, compositions, and methods

Patent 7989469 was granted and assigned to Cytokinetics on August, 2011 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Cytokinetics

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7989469

Date of Patent

August 2, 2011

Patent Application Number

12364394

Date Filed

February 2, 2009

Patent Primary Examiner

‌

Margaret D. Seaman

Patent abstract

Provided are certain chemical entities, and methods of use to modulate skeletal myosin, skeletal actin, skeletal tropomyosin, skeletal troponin C, skeletal troponin I, skeletal troponin T, and skeletal muscle, including fragments and isoforms thereof, as well as the skeletal sarcomere, and methods of use in the treatment of neuromuscular disorders, conditions having muscle wasting, claudication, frailty, metabolic syndrome, muscle atrophy associated with disuse, and muscle fatigue, and other indications.