An orthopedic device in the form of a cervical collar having height and circumferential adjustment includes an anterior portion and a posterior portion. The anterior portion includes a main support piece having depending projections configured to engage a height adjustment mechanism. Each of the anterior and posterior portions also includes a proximal support portion having a three-dimensional anatomically configured shape to support, immobilize, and stabilize an anatomical portion of a wearer. The anterior and/or posterior portion includes circumferential adjustment mechanisms to accommodate different sizes or differing degrees of swelling of anatomical portions.