US Patent 7968675 In vivo panning for ligands to radiation-induced molecules

Patent 7968675 was granted and assigned to Vanderbilt University on June, 2011 by the United States Patent and Trademark Office.

Overview Structured Data Issues Contributors Activity

Is a

Patent

Patent attributes

Current Assignee

Vanderbilt University

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7968675

Patent Inventor Names

Dennis E. Hallahan0

Shimian Qu0

Date of Patent

June 28, 2011

Patent Application Number

12111693

Date Filed

April 29, 2008

Patent Primary Examiner

‌

Hong Sang

Patent abstract

A method for identifying a molecule that binds an irradiated tumor in a subject and molecules identified thereby. The method includes the steps of: (a) exposing a tumor to ionizing radiation; (b) administering to a subject a library of diverse molecules; and (c) isolating from the tumor one or more molecules of the library of diverse molecules, whereby a molecule that binds an irradiated tumor is identified. Also provided are therapeutic and diagnostic methods using targeting ligands that bind an irradiated tumor.