Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Robert M. Dedinsky0
Bruce L. Zamost0
Date of Patent
June 28, 2011
0Patent Application Number
127013580
Date Filed
February 5, 2010
0Patent Primary Examiner
Patent abstract
The expression vectors and methods using an E. coli expression system for the large scale production of IL-29 are described. The vectors utilize the IL-29 coding sequence with specific changes in nucleotides in order to optimize codons and mRNA secondary structure for translation in E. coli. Also included are methods of producing, purifying and pegylating an IL-29 polypeptide.
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