Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Darren R. Link0
Jerome Bibette0
Keunho Ahn0
Andrew Griffiths0
David Weitz0
Date of Patent
June 28, 2011
Patent Application Number
10961695
Date Filed
October 8, 2004
Patent Citations Received
Patent Primary Examiner
Patent abstract
The invention describes a method for isolating one or more genetic elements encoding a gene product having a desired activity, comprising the steps of: (a) compartmentalising genetic elements into microcapsules; and (b) sorting the genetic elements which express the gene product having the desired activity; wherein at least one step is under microfluidic control. The invention enables the in vitro evolution of nucleic acids and proteins by repeated mutagenesis and iterative applications of the method of the invention.
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