Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Tobias Raum0
Jörg Volkland0
Patrick Bäuerle0
Stefan Pflanz0
John Lumsden0
Date of Patent
June 21, 2011
Patent Application Number
11916017
Date Filed
May 31, 2006
Patent Primary Examiner
Patent abstract
The invention relates to a humanized monoclonal antibody or fragment thereof which specifically binds to human interlukin-2 (IL2), whereby said humanized monoclonal antibody neutralizes the activity of human IL2 by binding to the human IL2 prior to, during, and/or subsequent to the binding of the human IL2 to the human IL2-receptor, and wherein the light chain variable region of the humanized monoclonal antibody comprises in its second framework region the contiguous amino acid sequence KAPKA at amino acid positions 42-46.
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