Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Carla Maria Gauss0
Richard Schumacher0
Jianguo Ma0
Wenge Xie0
Truc Minh Nguyen0
Ashok Tehim0
Brian Herbert0
Date of Patent
June 21, 2011
Patent Application Number
12857617
Date Filed
August 17, 2010
Patent Primary Examiner
Patent abstract
The present invention relates generally to the field of ligands for nicotinic acetylcholine receptors (nAChR), activation of nAChRs, and the treatment of disease conditions associated with defective or malfunctioning nicotinic acetylcholine receptors, especially of the brain. Further, this invention relates to novel compounds for example, indoles, 1H-indazoles, 1,2-benzisoxazoles, and 1,2-benzisothiazoles, which act as ligands for the α7 nAChR subtype, methods of preparing such compounds, compositions containing such compounds, and methods of use thereof.
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