Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Peter D. Senter0
Allen J. Ebens0
Brian E. Toki0
Mark X. Sliwkowski0
Paul Polakis0
Susan D. Spencer0
Svetlana O. Doronina0
Toni Beth Kline0
Date of Patent
June 21, 2011
Patent Application Number
11833959
Date Filed
August 3, 2007
Patent Citations Received
0
...
Patent Primary Examiner
Patent abstract
Auristatin peptides, including MeVal-Val-Dil-Dap-Norephedrine (MMAE) and MeVal-Val-Dil-Dap-Phe (MMAF), were prepared and attached to Ligands through various linkers, including maleimidocaproyl-val-cit-PAB. The resulting ligand drug conjugates were active in vitro and in vivo.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
