Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Christopher McGuigan0
Date of Patent
May 31, 2011
0Patent Application Number
105608870
Date Filed
July 20, 2004
0Patent Citations Received
...
Patent Primary Examiner
Patent abstract
Phosphoramidate derivatives of nucleotides and their use in the treatment of cancer are described. The base moieties of, for example, each of deoxyuridine, cytarabine, gemcitabine and citidine may be substituted at the 5-position. The phosphoramidate moiety has attached to the P atom an aryl-O moiety and an α-amino acid moiety. The α-amino acid moiety may correspond to or be derived from either a naturally occurring or a non-naturally occurring amino acid.
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