Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
John F. Leite0
Mahbod Hajivandi0
Robert Marshall Pope0
Xiquan Liang0
Date of Patent
May 10, 2011
Patent Application Number
11368996
Date Filed
March 7, 2006
Patent Primary Examiner
Patent abstract
The invention provides methods for quantifying biomolecules, such as polypeptides in mass spectrometric analysis. The methods include use of a biomolecule standard having at least one atomic isotope different than that of the naturally occurring isotopes in the biomolecule of interest. Methods of the present invention also include methods for quantifying biomolecules where the copy biomolecule standard is made by expressing the biomolecule using a recombinant cell. Further included are the biomolecule standards themselves, method for making such standards, kits, systems, reagents, and engineered cells relating to the use of biomolecule standards in mass spectrometric analysis.
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