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US Patent 7932085 Modified leukotoxin gene and protein

Patent 7932085 was granted and assigned to University of Guelph on April, 2011 by the United States Patent and Trademark Office.

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Patent
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Current Assignee
University of Guelph
University of Guelph
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
79320850
Patent Inventor Names
Judith N. Strommer0
Reggie Y. C. Lo0
Raymond W. H. Lee0
Doug Hodgins0
Patricia E. Shewen0
Date of Patent
April 26, 2011
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Patent Application Number
128335120
Date Filed
July 9, 2010
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Patent Primary Examiner
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Robert A Zeman
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Patent abstract

The present invention provides nucleic acid sequences encoding a modified leukotoxin protein, wherein the modification comprises the removal of nucleic acid sequences encoding amino acids within hydrophobic transmembrane domains of full length leukotoxin protein, preferably from Mannheimia haemolytica. The modified leukotoxin proteins are useful in vaccine compositions effective against Mannheimia haemolytica in animals.

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