Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Robert B. Darnell0
Date of Patent
April 19, 2011
0Patent Application Number
121686290
Date Filed
July 7, 2008
0Patent Primary Examiner
Patent abstract
The present invention relates to peptide vaccines, pharmaceutical compositions thereof, and associated methodologies that promote the immune-mediated regression of tumors expressing an onconeural antigen, e.g. a cdr-2 antigen, HuD antigen. The cancer peptide vaccines of the present invention are antigenic peptides capable of being faithfully presented on the MHC I complex of a target cell or antigen presenting cell. This external cellular presentation of these peptides promotes a specific cytotoxic T lymphocyte (CTL)-mediated immune response against tumor cells expressing these proteins, thereby, inducing immunological reactivity.
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