An adjusting device for adjusting the wear of the friction surface on the brake lining and brake disc of a pneumatic disc brake having a clamping device that is actuated by a rotary lever is provided. The device preferably can be inserted into a rotary spindle of the disc brake. An anti-friction body is positioned on both axial sides of a drive element, with the one bodies being a ramp coupling with a freewheeling function. The ramp coupling has coupling bushes and clamping balls, and the coupling bush on the driven side being supported on a spring sleeve. A conical seat is configured between the coupling bush and the sprung sleeve cooperates with the ramp coupling to preclude locking of the coupling bushes.