Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Michael Houghton0
Angelica Medina-Selby0
Doris Coit0
Mark Selby0
Date of Patent
February 15, 2011
0Patent Application Number
122870060
Date Filed
October 3, 2008
0Patent Primary Examiner
Patent abstract
Polypeptides comprising a mutant non-structural Hepatitis C virus useful in diagnostic and/or immunogenic compositions are disclosed, in which the mutant is an N-terminal mutation that functionally disrupts the catalytic domain of NS3. Polynucleotides encoding these polypeptides, host cells transformed with polynucleotides and methods of using the polypeptides and polynucleotides are also disclosed.
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