US Patent 7884116 Octahydronaphthalene derivative and medicine

Patent 7884116 was granted and assigned to Nippon Shinyaku on February, 2011 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Nippon Shinyaku

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

78841160

Patent Inventor Names

Naoyoshi Yamada0

Date of Patent

February 8, 2011

Patent Application Number

105968270

Date Filed

December 24, 2004

Patent Primary Examiner

‌

Patricia L Morris

Patent abstract

It is an object of the invention to provide a novel octahydronaphthalene derivative with an activity of inhibiting ICAM-4 expression and a pharmaceutically acceptable salt thereof. The invention encompasses, for example, agents for suppressing ICAM-1, therapeutic agents for inflammatory diseases, therapeutic agents for rheumatoid arthritis, immunosuppressive agents, and agents for suppressing cell growth, comprising N-(pyridin-3-ylmethyl)-(2E,4E)-5-[(1S,2S,4aR,6R,7S,8S,8aS)-7-hydroxy-2,6,8-trimethyl-1,2,4a,5,6,7,8,8a-octahydronaphthalen-1-yl]-2-methylpenta-2,4-dienamide as an active ingredient.