Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
January 25, 2011
Patent Application Number
11855193
Date Filed
September 14, 2007
Patent Primary Examiner
Patent abstract
Low molecular weight low molecular weight chitosan oligomers were able to self-assemble siRNA into nanosized particles, provide protection against enzymatic degradation, and mediate gene silencing that is stable over a long period of time in vitro. The control of structural variables in formulating complexes of siRNA with low molecular weight chitosans provides an efficient alternative delivery system for siRNA in vitro and in vivo.
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