Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Todd Richmond0
Jason Norton0
Kate Nuwaysir0
Roland Green0
Emile F. Nuwaysir0
Date of Patent
January 11, 2011
Patent Application Number
11346927
Date Filed
February 3, 2006
Patent Primary Examiner
Patent abstract
The present invention provides methods for optimizing oligonucleotide hybridization probes for use in basic and clinical research. Specifically, the invention involves hybridizing serially diluted genomic sample to the oligonucleotide probes on the array, such that a signal intensity is produced for each of the probes; computationally identifying optimized probes which exhibit signal intensities that correspond to the serial dilutions of genomic sample and are reproducibly strong relative to non-optimized probes.
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