Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
S. Stoney Simons, Jr.0
Yuanzheng He0
Date of Patent
January 11, 2011
0Patent Application Number
115108590
Date Filed
August 25, 2006
0Patent Primary Examiner
Patent abstract
The invention provides a new glucocorticoid receptor coactivator named STAMP (Steroid receptor coactivator-1 and Transcription intermediary factor-2 Associated Modulatory Protein) that can modulate transcription of glucocorticoid-, progesterone-, mineralocorticoid- and androgen-responsive genes. The invention also provides antibodies that can bind STAMP and modulate its activity. In addition, the invention provides antisense, ribozyme and siRNA STAMP nucleic acids that can modulate the expression of STAMP. Also provided are compositions and methods for modulating glucocorticoid-responsive gene expression and for treating a variety of diseases and conditions.
Timeline
No Timeline data yet.
Further Resources
No Further Resources data yet.
