Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Elisabeth Thomassen-Wolf0
Stefan Steidl0
Date of Patent
January 11, 2011
Patent Application Number
11914599
Date Filed
May 17, 2006
Patent Primary Examiner
Patent abstract
The present invention provides recombinant antigen-binding regions, antibodies and functional fragments thereof that are specific for GM-CSF, which plays an integral role in various disorders or conditions. These antibodies, accordingly, can be used to treat, for example, inflammatory diseases such as rheumatoid arthritis. Antibodies of the invention also can be used in the diagnostics field, as well as for further investigating the role of GM-CSF in the progression of various disorders. The invention also provides nucleic acid sequences encoding the foregoing antibodies, vectors containing the same, pharmaceutical compositions and kits with instructions for use.
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