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US Patent 7850946 Macrocyclic cyanine and indocyanine bioconjugates provide improved biomedical applications

Patent 7850946 was granted and assigned to Washington University in St. Louis on December, 2010 by the United States Patent and Trademark Office.

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Patent
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Current Assignee
Washington University in St. Louis
Washington University in St. Louis
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
78509460
Patent Inventor Names
Samuel Achilefu0
Yunpeng Ye0
Date of Patent
December 14, 2010
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Patent Application Number
105590000
Date Filed
June 1, 2004
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Patent Citations Received
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US Patent 11765340 Goggle imaging systems and methods
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US Patent 12121596 Near infrared fluorescent dyes, formulations and related methods
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US Patent 11712482 Near infrared fluorescent dyes, formulations and related methods
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Patent Primary Examiner
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D. L. Jones
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Patent abstract

The sensitivity and specificity of the optical modality can be enhanced by the use of highly absorbing compounds as contrast agents. Novel macrocyclic cyanine and indocyanine bioconjugates that absorb and emit light in the near infrared region of electromagnetic spectrum are disclosed. These compounds are especially useful for endoscopic, localized photoacoustic, and sonofluorescence imaging, detection and therapy of tumors and other abnormalities.

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