US Patent 7846428 Articular cartilage gene therapy with recombinant vector encoding BMP-7

Patent 7846428 was granted and assigned to Merial on December, 2010 by the United States Patent and Trademark Office.

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Patent

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Current Assignee

Merial

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7846428

Date of Patent

December 7, 2010

Patent Application Number

11867919

Date Filed

October 5, 2007

Patent Citations Received

‌

US Patent 11905531 Recombinant AAV vectors expressing osteoprotective genes, including HAS2 and lubricin, useful in the treatment of osteoarthritis and related joint conditions in mammals

Patent Primary Examiner

Quang Nguyen

Patent abstract

The present invention relates to recombinant vectors expressing the BMP-7 polypeptide in host cells and to pharmaceutical compositions comprising such recombinant vectors. The invention also encompasses methods for prevention and/or treatment of osteoarthritis in mammals, advantageously in humans, dogs, horses and cats, by intra-articular administration of the recombinant vectors and pharmaceutical compositions of the invention.

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