US Patent 7844333 Pacing therapy for transient ischemia treatment

Embodiments include methods and devices for detecting ischemia in a patient and treating the ischemia with a pacing therapy that increases cardiac efficiency, output, or both, without substantially increasing myocardial oxygen consumption. Such therapy may also be used to mitigate the adverse effects of decreased blood flow to the ischemic tissue by increasing the blood flow an oxygenation thereto.