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US Patent 7838699 Embolization using degradable crosslinked hydrogels

Patent 7838699 was granted and assigned to Biosphere Medical, Inc. on November, 2010 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
‌
Biosphere Medical, Inc.
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7838699
Patent Inventor Names
Hongmin Zhang7
Alexander Schwarz7
Date of Patent
November 23, 2010
Patent Application Number
10389708
Date Filed
March 14, 2003
Patent Citations Received
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US Patent 11759545 Polymer particles
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US Patent 11786630 Polymer particles
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US Patent 11801326 Polymeric treatment compositions
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US Patent 11911041 Embolic compositions
1
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US Patent 11857694 Particles
2
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US Patent 11926808 Array of micromolded structures for sorting adherent cells
3
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US Patent 11998563 Polymeric treatment compositions
4
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US Patent 12077622 Polymer particles
5
...
Patent Primary Examiner
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Robert A Wax
Patent abstract

One aspect of the present invention relates to a method of temporarily embolizing a blood vessel using a hydrolytically degradable crosslinked hydrogel as an embolus. In certain embodiments, the hydrolytically degradable crosslinked hydrogel substantially hydrolyzes only at about physiological pH. In certain embodiments of the method, the hydrolytically degradable crosslinked hydrogel is stable at low pH. In certain embodiments of the method, the hydrolytically degradable crosslinked hydrogel comprises a marker molecule, such as a dye, radiopaque, or an MRI-visible compound. It is to be understood that both the foregoing general description and the following detailed description are exemplary, and are intended to provide further explanation of the invention as claimed.

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