Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Manlio Palumbo0
Laura Iris Ferro0
Rodolfo Pescador0
Roberto Porta0
Barbara Gatto0
Date of Patent
November 23, 2010
0Patent Application Number
120156630
Date Filed
January 17, 2008
0Patent Primary Examiner
Patent abstract
The present research is directed to the identification of non-peptidic inhibitors of cathepsin G characterised by high levels of selectivity and which can be efficaciously used in the treatment and prophylaxis of inflammatory occurrences and procoagulant conditions. The cathepsin G-inhibiting aptamers according to the invention consist of linear DNA or polynucleotide sequences having a chain length of at least 60 nucleotides and being substantially not subjected to undergo efficient base pairing.
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