A drawer lock set includes a body with a tubular member and a block extends radially from an inner periphery of the tubular member. A cylinder and a core are received in the tubular member. The core includes a driving piece extending from a distal end thereof and is capable of driving a transmission member which is able to rotate a driving member. The driving member includes a protrusion which is slidably engaged with a groove defined in the dead bolt. The cylinder includes a first notch and a second notch in an outer periphery thereof and a 90-degree angular distance is defined between the first and second notches. The block is engaged with one of the first and second notches so as to set the position of the operational direction of the dead bolt with only one part replaced.