US Patent 7829696 siRNA targeting amyloid beta (A4) precursor protein (APP)

Patent 7829696 was granted and assigned to Dharmacon, Inc. on November, 2010 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Dharmacon, Inc.

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

7829696

Date of Patent

November 9, 2010

Patent Application Number

12590252

Date Filed

November 4, 2009

Patent Primary Examiner

‌

Brian Whiteman

Patent abstract

Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for APP.