Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
October 26, 2010
Patent Application Number
10985321
Date Filed
November 10, 2004
Patent Primary Examiner
Patent abstract
The present invention identifies that the expression of Activation Induced Deaminase (AID) or its homologues in cells confers a mutator phenotype and thus provides a method for generating diversity in a gene or gene product as well as cell lines capable of generating diversity in defined gene products. The invention also provides methods of modulating a mutator phenotype by modulating AID expression or activity.
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