Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Zoltán Tuba0
János Kiss0
László Terdy0
Sándor Mahó0
Endréné Magyari0
Date of Patent
October 19, 2010
0Patent Application Number
108797080
Date Filed
June 30, 2004
0Patent Primary Examiner
Patent abstract
The invention relates to a process for the synthesis of d-(17α)-13-ethyl-17-hydroxy-18,19-dinorpregn-4-ene-20-yn-3-one-oxime (also known as norelgestromin) via acetylation of d-norgestrel at position 17; oximation of the oxo group at position 3 of the obtained d-(17α)-13-ethyl-17-(acetyloxy)-18,19-dinorpregn-4-ene-20-yn-3-one; and then hydrolyzing the acetyloxy group at position 17 of the obtained d-(17α)-13-ethyl-17-(acetyloxy)-18,19-dinorpregn-4-ene-20-yn-3-oxime derivative, thereby obtaining norelgestromin.
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