Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
David Piwnica-Worms0
Vijay Sharma0
Date of Patent
September 28, 2010
0Patent Application Number
112079540
Date Filed
August 19, 2005
0Patent Citations Received
Patent Primary Examiner
Patent abstract
Novel blood-brain barrier permeant amyloid-targeting peptides and peptide conjugates are described. The peptide conjugates include a radioisotope or other label in a stable complex that translocates across brain capillary endothelial cell monolayers. The labeled peptide conjugate binds to amyloid plaques (Aβ) associated with Alzheimer's disease, and is useful for the targeted delivery of therapeutic and diagnostic molecules into the brain.
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