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US Patent 7795002 Production of galactosylated glycoproteins in lower eukaryotes

Patent 7795002 was granted and assigned to Glycofi, Inc. on September, 2010 by the United States Patent and Trademark Office.

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Current Assignee
Glycofi, Inc.
Glycofi, Inc.
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
77950020
Patent Inventor Names
Piotr Bobrowicz0
Stefan Wildt0
Robert Davidson0
Tillman Ulf Gerngross0
Stephen Robin Hamilton0
Byung-Kwon Choi0
Juergen Hermann Nett0
Date of Patent
September 14, 2010
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Patent Application Number
111080880
Date Filed
April 15, 2005
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Patent Primary Examiner
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Anand U Desai
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Patent abstract

The present invention provides a novel lower eukaryotic host cell producing human-like glycoproteins characterized as having a terminal β-galactose residue and essentially lacking fucose and sialic acid residues. The present invention also provides a method for catalyzing the transfer of a galactose residue from UDP-galactose onto an acceptor substrate in a recombinant lower eukaryotic host cell, which can be used as a therapeutic glycoprotein.

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