Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
T. Ashton Cropp0
J. Christopher Anderson0
Jason W. Chin0
Peter G. Schultz0
Date of Patent
September 14, 2010
Patent Application Number
11978172
Date Filed
October 26, 2007
Patent Primary Examiner
Patent abstract
This invention provides compositions and methods for producing translational components that expand the number of genetically encoded amino acids in eukaryotic cells. The components include orthogonal tRNAs, orthogonal aminoacyl-tRNA synthetases, orthogonal pairs of tRNAs/synthetases and unnatural amino acids. Proteins and methods of producing proteins with unnatural amino acids in eukaryotic cells are also provided.
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