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US Patent 7790420 Method for determining protein solubility

Patent 7790420 was granted and assigned to European Molecular Biology Laboratory on September, 2010 by the United States Patent and Trademark Office.

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Current Assignee
European Molecular Biology Laboratory
European Molecular Biology Laboratory
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
77904200
Patent Inventor Names
Franck Tarendeau0
Darren Hart0
Date of Patent
September 7, 2010
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Patent Application Number
117008200
Date Filed
February 1, 2007
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Patent Primary Examiner
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Amber D Steele
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Patent abstract

The present invention relates to methods of screening for expression of a soluble candidate protein within an expression library of candidate proteins. The method involves fusing each candidate protein in the library to a peptide substrate and identifying cells that express soluble candidate protein by detecting enzymatic modification of the peptide substrate.

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