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US Patent 7781487 Di-fluoro containing compounds as cysteine protease inhibitors

Patent 7781487 was granted and assigned to Virobay on August, 2010 by the United States Patent and Trademark Office.

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Patent abstract

The present invention is directed to compounds that are inhibitors of cysteine proteases, in particular, cathepsins B, K, L, F, and S, and are therefore useful in treating diseases mediated by these proteases. The present invention is directed to pharmaceutical compositions comprising these compounds and processes for preparing them.

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