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US Patent 7781399 Immunogenic compositions and methods of use

Patent 7781399 was granted and assigned to Artificial Cell Technologies on August, 2010 by the United States Patent and Trademark Office.

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Current Assignee
Artificial Cell Technologies
Artificial Cell Technologies
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7781399
Date of Patent
August 24, 2010
Patent Application Number
12573366
Date Filed
October 5, 2009
Patent Primary Examiner
‌
Christina Bradley
Patent abstract

Disclosed herein are immunogenic compositions comprising a multilayer film comprising two or more layers of polyelectrolytes, wherein adjacent layers comprise oppositely charged polyelectrolytes. A first layer polyelectrolyte comprises an antigenic polypeptide comprising one or more surface adsorption regions covalently linked to one or more antigenic determinant regions, wherein the antigenic polypeptide and the one or more surface adsorption regions have the same polarity. The immunogenic compositions may be employed in methods of eliciting an immune response in a vertebrate organism.

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