Is a
Patent attributes
Patent Jurisdiction
Patent Number
Date of Patent
August 24, 2010
Patent Application Number
11017771
Date Filed
December 22, 2004
Patent Primary Examiner
Patent abstract
Disclosed herein is a pharmacophore model for inhibiting anthrax lethal factor protease activity which comprises a first aromatic center A, a second aromatic center B, a first polar center C, a second polar center D, a third polar center E, and a neutral linker F. Also disclosed are small molecules fitting the pharmacophore model and compositions and methods of using thereof.
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