Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Robert William Kavash0
Marc René de Jonge0
Michael Joseph Kukla0
Paul Adriaan Jan Janssen0
Alain Krief0
Bart Lieven Daniel De Corte0
Donald William Ludovici0
Jan Heeres0
...
Date of Patent
July 27, 2010
0Patent Application Number
112258390
Date Filed
September 13, 2005
0Patent Primary Examiner
Patent abstract
The present invention concerns compounds of formula (A1)(A2)N—R1 (I), the N-oxide forms, the pharmaceutically acceptable addition salts, the quaternary amines and stereochemically isomeric forms thereof, wherein R1 is substituted C1-6alkyl; —S(═O)—R8; —S(═O)2—R8; C7-12alkylcarbonyl; optionally substituted C1-6alkyloxycarbonylC1-6alkylcarbonyl; with R8 being C1-6alkyl, aryl1 or Het1; (A1)(A2)N— is the covalently bonded form of the corresponding intermediate of formula (A1)(A2)N—H, which is a HIV replication inhibiting pyrimidine of formula
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