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US Patent 7754737 Diaminoalkane aspartic protease inhibitors

Patent 7754737 was granted and assigned to Vitae Pharmaceuticals on July, 2010 by the United States Patent and Trademark Office.

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Patent
Patent
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Patent attributes

Current Assignee
Vitae Pharmaceuticals
Vitae Pharmaceuticals
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Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
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Patent Number
77547370
Patent Inventor Names
Zhenrong Xu0
Salvacion Cacatian0
Suresh B. Singh0
Wei Zhao0
Alexey V. Ishchenko0
Colin M. Tice0
David A. Claremon0
Gerard McGeehan0
...
Date of Patent
July 13, 2010
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Patent Application Number
116645580
Date Filed
October 7, 2005
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Patent Primary Examiner
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Rebecca L Anderson
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Patent abstract

Diaminoalkanes of Formula I have now been found which are orally active and bind to aspartic proteases to inhibit their activity. They are useful in the treatment or amelioration of diseases associated with elevated levels of aspartic protease activity. The invention also relates to a method for the use of the compounds of Formula I in ameliorating or treating aspartic protease related disorders in a subject in need thereof comprising administering to said subject an effective amount of a compound of Formula I.

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