Is a
Patent attributes
Current Assignee
Patent Jurisdiction
Patent Number
Patent Inventor Names
Stephen Scaringe0
Devin Leake0
William Marshall0
Steven Read0
Anastasia Khvorova0
Angela Reynolds0
Date of Patent
June 29, 2010
0Patent Application Number
124620290
Date Filed
July 28, 2009
0Patent Primary Examiner
Patent abstract
Efficient sequence specific gene silencing is possible through the use of siRNA technology. By selecting particular siRNAs by rational design, one can maximize the generation of an effective gene silencing reagent, as well as methods for silencing genes. Methods, compositions, and kits generated through rational design of siRNAs are disclosed including those directed to nucleotide sequences for IRAK4.
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