US Patent 7737293 Amide forming chemical ligation

Patent 7737293 was granted and assigned to Regents of the University of California on June, 2010 by the United States Patent and Trademark Office.

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Is a

Patent

Patent attributes

Current Assignee

Regents of the University of California

Patent Jurisdiction

United States Patent and Trademark Office

Patent Number

77372930

Patent Inventor Names

Ryan M. Fox0

Jeffrey W. Bode0

Date of Patent

June 15, 2010

Patent Application Number

122684250

Date Filed

November 10, 2008

Patent Primary Examiner

‌

Shailendra Kumar

Patent abstract

An amide is formed by reacting an α-ketoacid or salt thereof in a decarboxylative condensation reaction with an amine or salt thereof comprising a nitrogen covalently bound to an atom selected from oxygen, nitrogen, and sulfur. The amide bond is formed between the α-carbon of the ketoacid and the nitrogen of the amine. The α-ketoacid can be formed using a novel sulfur reagent.