Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Mark Nguyen Ho0
Evan R. Lewis0
Fabiana N. Fonseca0
Date of Patent
June 15, 2010
Patent Application Number
11299265
Date Filed
December 7, 2005
Patent Primary Examiner
Patent abstract
Compositions comprising one or more practically insoluble proteasome inhibitors and a cyclodextrin, particularly a substituted cyclodextrin, substantially increase the solubility of these proteasome inhibitors and facilitate their administration. Such compositions optionally comprise a buffer. Methods of treatment using such compositions are also disclosed.
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