Patent 7718688 was granted and assigned to Auckland Uniservices Limited on May, 2010 by the United States Patent and Trademark Office.
The present invention relates generally to nitro-1,2-dihydro-3H-benzo[e]indoles and related analogues, to their preparation, and to their use as hypoxia-selective drugs and radiosensitizers for cancer therapy, both alone or in combination with radiation and/or other anticancer drugs.