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US Patent 7718647 Substituted azepine derivatives as serotonin receptor modulators

Patent 7718647 was granted and assigned to Athersys on May, 2010 by the United States Patent and Trademark Office.

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Patent abstract

The present invention generally relates to a series of compounds, to pharmaceutical compositions containing the compounds, and to use of the compounds and compositions as therapeutic agents. More specifically, compounds of the present invention are hexahydroazepinoindole and octahydroazepinoindole compounds. These compounds are serotonin receptor (5-HT) ligands and are useful for treating diseases, disorders, and conditions wherein modulation of the activity of serotonin receptors (5-HT) is desired (e.g. anxiety, depression and obesity).

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