Is a
Patent attributes
Patent Jurisdiction
Patent Number
Patent Inventor Names
Sergey G. Lokhov0
Michael J. Singer0
Nicolaas M. J. Vermeulen0
Robert O. Dempcy0
Alexander A. Gall0
Igor V. Kutyavin0
Irina A. Afonina0
Date of Patent
May 11, 2010
0Patent Application Number
101769720
Date Filed
June 18, 2002
0Patent Primary Examiner
Patent abstract
Software systems and methods for predicting the melting temperature (Tm) and other characteristics of oligonucleotides, including modified oligonucleotides. Modified oligonucleotides are provided containing bases selected from unsubstituted and 3-substituted pyrazolo[3,4-d]pyrimidines and 5-substituted pyrimidines, and optionally have attached minor groove binders and reporter groups.
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