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US Patent 7699767 Multiple laminar flow-based particle and cellular separation with laser steering

Patent 7699767 was granted and assigned to Arryx on April, 2010 by the United States Patent and Trademark Office.

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Patent
Patent

Patent attributes

Current Assignee
‌
Arryx
Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
Patent Number
7699767
Patent Inventor Names
Amy Anderson0
Joseph Plewa0
Lewis Gruber0
Neil Harris Rosenbaum0
Daniel Mueth0
Jessica Shireman0
Date of Patent
April 20, 2010
Patent Application Number
12213109
Date Filed
June 13, 2008
Patent Citations Received
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US Patent 11833515 Microfluidic channel networks for partitioning
0
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US Patent 12059679 Methods and devices for sorting droplets and particles
0
Patent Primary Examiner
‌
Kiet T Nguyen
Patent abstract

The invention provides a method, apparatus and system for separating blood and other types of cellular components, and can be combined with holographic optical trapping manipulation or other forms of optical tweezing. One of the exemplary methods includes providing a first flow having a plurality of blood components; providing a second flow; contacting the first flow with the second flow to provide a first separation region; and differentially sedimenting a first blood cellular component of the plurality of blood components into the second flow while concurrently maintaining a second blood cellular component of the plurality of blood components in the first flow. The second flow having the first blood cellular component is then differentially removed from the first flow having the second blood cellular component. Holographic optical traps may also be utilized in conjunction with the various flows to move selected components from one flow to another, as part of or in addition to a separation stage.

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