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US Patent 7695752 Target activated microtransfer

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Patent
Patent
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Patent attributes

Patent Jurisdiction
United States Patent and Trademark Office
United States Patent and Trademark Office
0
Patent Number
76957520
Patent Inventor Names
Thomas J. Pohida0
Michael R. Emmert-Buck0
Robert F. Bonner0
Rodrigo F. Chuaqui0
Michael Anthony Tangrea0
Date of Patent
April 13, 2010
0
Patent Application Number
112028480
Date Filed
August 12, 2005
0
Patent Primary Examiner
‌
Nelson Yang
0
Patent abstract

A device for performing target activated transfer that includes a mounting surface for mounting a tissue sample; and a light source positioned to substantially uniformly irradiate both stained and unstained regions of the tissue sample with light energy that activates the reagent to selectively adhere the stained regions to a transfer surface. Also described is an automated system for transferring tissue from a tissue sample to a transfer substrate. The system includes means for holding a tissue section that includes targets specifically stained with an absorptive stain thereby resulting in a stained tissue surface, and a flexible transfer film that includes a lower thermoplastic layer in sufficient thermal contact with the stained tissue surface; an irradiating assembly configured to provide a predetermined uniform light dose to the entire tissue section; and means for applying a constant pressure to the transfer film during irradiation.

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